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  • 19-September-2019

    English

    Draft Guidance and Review Documents/Monographs

    The OECD Guidelines for the Testing of Chemicals are a unique tool for assessing the potential effects of chemicals on human health and the environment. They are regularly updated with the assistance of thousands of national experts from OECD member countries. The current deadline for comments is set on 19 September 2019 for the Draft Guidance Document dissolution rate and dispersion stability of nanomaterials.

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  • 19-August-2019

    English

    Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

    Latest releases: The 1st report describes the linkage between inhibition of complex I of the mitochondrial respiratory chain and motor deficit as in parkinsonian disorders. The 2nd report links chronic binding of antagonist to N-methyl-D-aspartate receptors during brain development leading to neurodegeneration. The 3rd report details the linkage between binding and activation of androgen receptor leading to reproductive dysfunction.

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  • 31-July-2019

    English

    OECD Test Guidelines Programme

    The OECD Guidelines for the testing of chemicals are a collection of the most relevant internationally agreed testing methods used by governments, industry and independent laboratories to assess the safety of chemical products. The current work plan is now available.

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  • 24-July-2019

    English

    OECD Series on Principles of Good Laboratory Practice (GLP) and Compliance Monitoring

    The purpose of this document is to give guidance to Receiving Authorities on the evaluation of the GLP compliance status of nonclinical safety studies submitted for regulatory purposes. This guidance does not address the scientific evaluation and interpretation of the submitted data or the risk assessment based on these data.

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  • 24-July-2019

    English

    Series on Testing and Assessment: publications by number

    Children are more vulnerable than adults to environmental hazards, such as those presented by chemicals, due to their physiological differences and unique behaviours. The OECD is working to bring together knowledge and experiences to reduce risks to children’s health from chemicals. This report reviews and updates available information with a focus on direct object mouthing to ensure that potential risks for children are addressed.

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  • 22-July-2019

    English

    Global Forum on Environment - Plastics in a Circular Economy: Design of Sustainable Plastics from a Chemicals Perspective

    Policy instruments can be applied to improve the sustainability of plastics, including regulations, market-based instruments, information and voluntary tools. The report reviews the use of these instruments, provides good practice examples, such as product taxes and charges, eco-design standards, extended producer responsibility and environmental product labels, as well as discussing opportunities for their future applications.

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  • 19-July-2019

    English

    Section 4: Health Effects

    Consult the January and February 2019 deadlines for comment of various OECD Guidelines for the Testing of Chemicals: in Vitro 3T3 NRU phototoxicity test; Vitrigel Eye Irritancy Test Method; in vitro Macromolecular Test Method for Eye Hazard Potential; and In Chemico Skin Sensitisation Assays addressing the AOP Key Event of covalent binding to proteins.

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  • 17-July-2019

    English, PDF, 5,364kb

    OECD work on Chemical Safety and Biosafety brochure 2019-2020

    This new edition of the OECD work on Chemical Safety and Biosafety highlights the activities, results and ongoing projects as outlined by the 2019-2020 work programme.

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  • 17-July-2019

    English

    Release of the Global Harmonised Submission Transport Standard (GHSTS) version 2.0

    GHSTS is a standardised set of technical specifications for assembling electronic files for pesticide registration in a predefined manner. Once assembled according to the GHSTS, the dossier files can be transferred from a business to a regulatory authority and can be used in a regulatory process. Version 2.0 includes improved lifecycle management of documents over a series of submissions for one pesticide (or other) regulatory action.

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  • 26-June-2019

    English

    OECD Biotechnology Newsletter Updates

    Read our newsletter to stay up-to-date with all the latest OECD work on biotechnology.

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