The following publications provide validation reports, peer-review reports, background review documents and supporting documents for methods and approaches that have been adopted as OECD Test Guidelines or may become OECD Test Guidelines with additional work underway.
Validation reports for methods developed as Test Guidelines
No. 384 Epidermal Sensitisation Assay (EpiSensA) Validation Study Report
No. 380 Validation of the Juvenile Medaka anti-androgen screening assay (JMASA)
No. 353 Validation of the Rapid Androgen Disruption Activity (RADAR) assay for the detection of androgen axis active substances, described in OECD Test Guideline 251
No. 352 Validation Report on Particle and Fibre Size Distribution Measurements of Nanomaterials. Supporting TG 125 on Particle Size and Particle Size Distribution of Nanomaterials
No. 339 Validation study report and independent peer-review report for inclusion of keraskin skin irritation test to the Test Guideline 439 on in vitro Skin Irritation: reconstructed human epidermis test method
No. 337 Validation Study Report of the Kinetic Direct Peptide Reactivity Assay (kDPRA) in Test Guideline 442C
No. 335 Report of the validation study of the EASZY Assay in Test Guideline 250
No. 334 Validation report for the Test Guideline 249 on Fish cell line acute toxicity - the RTgillW1 cell line assay
No. 316 The in vivo erythrocyte Pig-a gene mutation assay – Part 2 – Validation report
No. 304 Second Edition, Validation Study Report Of The Amino Acid Derivative Reactivity Assay (ADRA) No. 302 Validation Report Of The Xenopus Eleutheroembryonic Thyroid Signaling Assay (Xeta) For The Detection Of Thyroid Active Substances
No. 301 Report of the Validation Study and Report Of the Peer Review of the Validation of the Vitrigel Eye Irritancy Test Method in Test Guideline 49
No. 300 Report Of The Validation Study Of The Mctt Human Corneal-Like Epithelium Eye Irritation Test Model And Report Of The Validation Peer-Review
No. 283 Report of The Validation Study of the Local Lymph Node Assay BrdU-FCM (LLNA: BrdU-FCM) Test Method
No. 281 Validation Report of the two new Test Guidelines on Determination of In Vitro Intrinsic Clearance Using Cryopreserved Rainbow Trout Hepatocytes or Liver S9 Sub-Cellular Fractions
No. 277 Report of the Validation Study for the Standardisation of a 10 day feeding test on Honey Bees as describer in OECD Test Guideline 245
No. 276 Report of the validation study supporting the development of the draft (new) TG 318 on dispersion behaviour of nanomaterials in different environmental media
No. 267 Validation report for the international validation study on the IL-8 Luc assay as a test evaluating the skin sensitizing potential of chemicals conducted by the IL-8 Luc Assay
No. 266 Effects of chemicals on waste water treatment: Final validation study of the protozoan activated sludge test to establish an OECD Test Guideline
No. 241 Report of the First and Second Validation Studies for AR STTA Assays to Detect Androgenic and Anti-androgenic Activities of Chemicals
No. 240 Draft report of the validation of the (anti-) ERα CALUX bioassay: U2-OS cells Transcriptional ERalpha CALUX- assay for the detection of estrogenic and anti-estrogenic chemicals for inclusion in TG455
No. 236 Lymnea validation report
No. 235 Potamopyrgus validation report
No. 226 Integrated Summary Report: Validation of Two Binding Assays Using Human Recombinant Estrogen Receptor Alpha (hrERa), Annex 1, Annex 2, Annex 3
No. 225 Report of the Inter-Laboratory Validation for Stably Transfected Transactivation Assay to Detect Estrogenic and Anti-estrogenic Activity
No. 208 BHAS 42 Cell Transformation Assay Validation Study Report
No. 196 Report of the JACVAM Initiative International Validation Studies of the in vivo Rodent Alkaline Comet Assay for the Detection of Genotoxic Carcinogens
No. 195 Report of the JACVAM Initiative International Pre-Validation Studies of the in vivo Rodent Alkaline Comet Assay for the Detection of Genotoxic Carcinogens
No. 191 Validation Report of a Ring Test for the OECD 305 Dietary Exposure Bioaccumulation Fish Test, Additional Report Including Results Using a Lower Feeding Rate
No. 179 Validation Report (Phase 2) for the Zebrafish Embryo Toxicity Test [Annexes]
No. 175 Validation Report of a Ring Test for the OECD 305 Dietary Exposure Bioaccumulation Fish Test (Part 1) with Additional Report Including Comparative Analysis of Trout and Carp Results (Part II)
No. 159 Validation Report for the Skin Irritation Test Method using LabCyte EPI-MODEL24
No. 158 Report of Progress on the Interlaboratory Validation of the OECD Harpacticoid Copepod Development and Reproduction Test
No. 157 Validation Report (Phase 1) for the Zebrafish Embryo Toxicity Test: Part I - Part II
No. 154 Validation Report: Validation of Efficacy Methods for Antimicrobials Used on Hard Surfaces: Part I, Part II
No. 149 Validation Report of the Balb/c 3T3 Cell Transformation Assay (2011)
No. 147 Syrian Hamster Embryonic (SHE) Cell PH 7.0 Cell Transformation Assay Prevalidation Study Report (2011)
No. 146 Syrian Hamster Embryonic (SHE) Cell PH 6.7 Cell Transformation Assay Prevalidation Study Report (2011)
No. 145 Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays: Retrospective Performance Assessment
No. 144 Validation Report for the Acute Chironomid Assay
No. 142 Report of the Phase 2 of the Validation of the Fish Sexual Development Test for the Detection of Endocrine Active Substances
No. 141 Report of the Phase 1 of the Validation of the Fish Sexual Development Test for the Detection of Endocrine Active Substances
No. 136 Validation Report of the Chironomid Full Life-Cycle Toxicity Test
No. 134 Report of the Validation of a Soil Bioaccumulation Test with Terrestrial Oligochaetes by an International ring test
No. 132 Report of the Multi-Laboratory Validation of the H295R Steroidogenesis Assay to Identify Modulators
No. 131 Report of the Test Method Validation of Avian Acute Oral Toxicity Test (OECD Test Guideline 223)
No. 128 Validation Rreport on the 21-day Androgenised Female Stickleback Screening Assay
No. 110 Report of the Validation Peer Review for the Weanling Hershberger Bioassay and Agreement of the Working of National Coordinators of the Test Guidelines Programme on the Follow-up of this Report
No. 108 Report of the Validation of the Hershberger Bioassay (Weanling Model)
No. 94 Report of the Validation Peer Review for the 21-day Fish Endocrine Screening Assay and Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-up of the Report
No. 93 Report of the Validation of an Enhancement of OECD TG 211: Daphnia Magna Reproduction Test
No. 92 Report of the Validation Peer Review for the Amphibian Metamophosis Assay and Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-up of this Report
No. 91 Report of the Validation of the Amphibian Metamorphosis Assay (Phase 3)
No. 86 Report of the OECD Validation of the Rodent Hershberger Bioassay - Phase 2: Testing of Androgen Agonists, Androgen Antagonists and a 5 α-Reductase Inhibitor in Dose Response Studies by Multiple Laboratories
No. 85 Report of the Validation Peer Review for the Hershberger Bioassay, and the Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-up of this Report
No. 81 Summary Report of the Validation Peer Review for the Updated Test Guideline 407, and Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on the Follow-up of this Report
No. 79 Validation Report of the Full Life-cycle Test with the Harpacticoid Copepods Nitocra Spinipes and Amphiascus Tenuiremis and the Calanoid Copepod Acartia Tonsa - Phase 1
No. 78 Final Report of the Validation of the 21-day Fish Screening Assay for the Detection of Endocrine Active Substances - Phase 2: Testing Negative Substances
No. 77 Final Report of the Validation of the Amphibian Metamorphosis Assay - Phase 2: Multi-chemical Interlaboratory Study
No. 76 Final Report of the Validation of the Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances - Phase 1: Optimisation of the Test Protocol
No. 73 Report of the Validation of the Rat Hershberger Assay - Phase 3: Coded Testing of Androgen Agonists, Androgen Antagonists and Negative Reference Chemicals by Multiple Laboratories. Surgical Castrate Model Protocol.
No. 67 Report of the Uterotrophic Bioassay: Additional Data Supporting the Test Guideline on the Uterotrophic Bioassay in Rodents
No. 66 OECD Report of the Validation of the Rodent Uterotrophic Bioassay - Phase 2: Testing of Potent and Weak Oestrogen Agonists by Multiple Laboratories
No. 65 OECD Report of the Initial Work Towards the Validation of the Rodent Uterothophic Assay - Phase 1
No. 62 Final OECD Report of the Initial Work Towards the Validation of the Rat Hershberger Assay - Phase 1: Androgenic Response to Testosterone Propionate, and Anti-Androgenic Effects of Flutamide
No. 61 Report of the Validation of the 21-day Fish Screening Assay for the Detection of Endocrine Active Substances - Phase 1B
No. 60 Report of the Initial Work Towards the Validation of the 21-day Fish Screening Assay for the Detection of Endocrine Active Substances - Phase 1A
No. 59 Report of the Validation of the Updated Test Guideline 407 - Repeat Dose 28-day Oral Toxicity Study in Laboratory Rats [Annexes]
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