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Publications & Documents


  • 26-June-2019

    English

    Webinar video recording on Risk Reduction Initiatives for Per- and Polyfluoroalkyl substances in Canada and in the United States

    On 15 May 2019, Eeva Leinala of the OECD Environment Directorate, Sandi Moser of the Environment and Climate Change Canada, and Hannah Holsinger of the EPA presented the latest Risk Reduction Initiatives for Per- and Polyfluoroalkyl substances undertaken by Canada and the United States.

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  • 18-June-2019

    English

    Test No. 431: In vitro skin corrosion: reconstructed human epidermis (RHE) test method

    The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight of evidence determination using other existing information. The test protocol may also provide an indication of the distinction between severe and less severe skin corrosives. This Test Guideline does not require the use of live animals or animal tissue for the assessment of skin corrosivity. The test material (solid or liquid) is applied uniformly and topically to a three-dimensional human skin model, comprising at least a reconstructed epidermis with a functional stratum corneum. Two tissue replicates are used for each treatment (exposure time), and for controls. Corrosive materials are identified by their ability to produce a decrease in cell viability below defined threshold levels at specified exposure periods. Coloured chemicals can also be tested by used of an HPLC procedure. The principle of the human skin model assay is based on the hypothesis that corrosive chemicals are able to penetrate the stratum corneum by diffusion or erosion, and are cytotoxic to the underlying cell layers.

  • 13-June-2019

    English

    Guiding Principles on Good Practices for the Availability/Distribution of Protected Elements in OECD Test Guidelines

    This document describes good practices for the licensing of protected elements included in OECD Test Guidelines (TGs). Transparency and communication are needed around protected elements resulting from innovation in sciences and techniques that are gradually integrated in OECD TGs. This Guidance specifies the information required from a test method developer when submitting a proposal for a new TG that contains protected elements. This document contains a broad overview of the intellectual property and similar protections that affect the OECD TG Programme. Laws governing intellectual property and similar rights vary widely from jurisdiction to jurisdiction; anyone seeking to answer specific questions about the interpretation of the concepts in this paper in a specific jurisdiction must seek the advice of a specialised lawyer.

  • 24-May-2019

    English

    Complementing Document to the Emission Scenario Document on Plastic Additives: Plastic Additives during the Use of End Products

    This OECD Emission Scenario Document (ESD) is a complement document to the Emission Scenario Document on Plastic Additives, ESD No. 3, and provides information on the sources, use patterns and release pathways of chemicals used as additives in plastics to assist in the estimation of releases of chemicals into the environment.

  • 15-May-2019

    English

    Webinar: Register to find out the latest Risk Reduction Initiatives for PFASs in Canada and the United States

    Join us on 15 May 2019 @ 1 pm (Paris time) / 7 am (EST time) to learn about the latest Risk Reduction Initiatives for Per- and Polyfluoroalkyl Substances undertaken by Canada and the United States.

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  • 26-February-2019

    English

    Watch the video recording on Best Environmental Practices for Class B Firefighting Foams

    On 29 January 2019, Eeva Leinala of the OECD Environment Directorate and Thomas Cortina from the Fire Fighting Foam Coalition and Mitch Hubert from Perimeter Solutions have addressed Best Environmental Practices for Class B Firefighting Foams in the context of management of per- and polyfluoroalkyl Substances (PFASs).

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  • 20-February-2019

    English

    Adoption of the Recommendation on Countering the Illegal Trade of Pesticides

    Today, OECD Council adopted the Recommendation on Countering the Illegal Trade of Pesticides to strengthen cooperation between countries and inspectors and identify illegal pesticides throughout their lifecycle with a Best Practice Guidance.

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  • 13-February-2019

    English

    Mutual Acceptance of Data (MAD)

    The OECD has developed the Mutual Acceptance of Data (MAD), a multilateral agreement which allows participating countries (including non members) to share the results of various non-clinical tests done on chemicals using OECD methods and principles. MAD reduces duplicative testing, allows governments to work together when assessing chemicals, and saves government and industry resources.

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  • 7-February-2019

    English

    Customisation Opportunities of IUCLID for the Management of Chemical Data

    The IUCLID (International Uniform ChemicaL Information Database) can be customised to manage chemical data in different contexts and is a platform employing globally harmonised data elements pertinent to chemicals. The version 6 of IUCLID software released in 2016 allows for greater customisation of IUCLID and for extension and integration with other tools. For example, the standard IUCLID data elements can be extended to capture specific information for specific legislative data needs before they are added to the OHTs. This document describes four main elements related to the customisation of IUCLID including how the IUCLID format can be configured and customised, the main IUCLID features and add-ons, integration with other systems and development of alternative user interfaces. The document also outlines how customisation of these different elements requires different expertise and resources. It incorporates user stories regarding customisation of and data migration to IUCLID from ECHA, Australia, and Canada. Following an update of the IUCLID 6 software, a second edition of the report was released in June 2021 to reflect the most recent features and processes.
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