By Date

The costs and benefits of regulating chemicals

The OECD has set up the Surveys on Willingness-to-Pay to Avoid Negative Chemicals-Related Health Impacts (SWACHE) project to establish comparable values for the willingness-to-pay to avoid negative health effects due to exposure to chemicals. The health effects valued include asthma, infertility, IQ loss, chronic kidney disease, and very low birth weight.

Publications in the series on Pollutant Release and Transfer Registers

Countries are taking action against toxic chemicals emitted into air, water and land by industry. How can countries track progress made towards this target? The new OECD report looks at Pollutant Release and Transfer Registers data as a means to track toxic releases to monitor chemical pollution in order to meet the United Nations Sustainable Development Goal Target 12.4.

Safety of novel foods and feeds and on the harmonisation of regulatory oversight in biotechnology

These two documents compile information on activities related to the assessment of the safety of products derived from modern biotechnology, environmental safety (biosafety) and the safety of novel foods and feeds, at the international level between April 2021 and May 2022. The information was provided by OECD Members, partner countries and observer organisations participating in the work.

OECD Good Laboratory Practice: Frequently asked questions (FAQ)

GLP issues raised by testing labs are covered in this comprehensive list of questions and answers, recently updated with questions related to: Test Facility organisation and personnel, Quality Assurance, Equipment and computerized systems, Test items, reference items and samples/specimens (Biologicals, GMOs, etc.), SOPs, Management of the study, Histopathology, Archives and E-Archives and Monitoring Test Facility compliance by GLP CMAs.

Safety Assessment of Transgenic Organisms: OECD Consensus Documents

The OECD biosafety consensus documents identify elements of scientific information used in the environmental safety and risk assessment of transgenic organisms which are common to OECD member countries.

Risks from Natural Hazards at Hazardous Installations (Natech)

Natural Hazards Triggering Technological Accidents (Natech) are accidents triggered by the impact of a natural hazard, such as earthquake, flood, or storm, on a hazardous installation, and which involves the release of hazardous substances, fires or explosions. This brochure aims to raise awareness of Natech risks and the challenges associated with their management.

Test No. 455: Performance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists and Antagonists

Guidance on Key Considerations for the Identification and Selection of Safer Chemical Alternatives

As the demand for safer chemicals grows, the field of alternatives assessment is becoming increasingly important in guiding the transition towards safer, less toxic alternatives. A major limitation that can hinder efforts is the lack of consistent criteria for defining “safer" alternatives. This guidance outlines key considerations for the identification and selection of safer alternatives.

Substitution of hazardous chemicals

As the demand for safer chemicals grows, the field of alternatives assessment is becoming increasingly important in guiding the transition towards safer, less toxic alternatives. A major limitation that can hinder efforts is the lack of consistent criteria for defining “safer" alternatives. This guidance outlines key considerations for the identification and selection of safer alternatives.

OECD Work Related to Endocrine Disrupters

The OECD has published the Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.