Report on Considerations from Case Studies on Integrated Approaches for Testing and
Assessment (IATA) - First Review Cycle (2015)
Case Studies on Grouping Methods as a Part of IATA
OECD member countries have been making efforts to expand the use of alternative methods
in assessing chemicals. The OECD has been developing guidance documents and tools
for the use of alternative methods such as (Q)SAR, chemical categories and Adverse
Outcome Pathways (AOPs) as a part of Integrated Approaches for Testing and Assessment
(IATA). There is a need for the investigation of the practical applicability of these
methods/tools for different aspects of regulatory decision-making, and to build upon
case studies and assessment experience across jurisdictions. The objective of the
IATA Case Studies Project is to increase experience with the use of IATA by developing
case studies, which constitute examples of predictions that are fit for regulatory
use. The aim is to create common understanding of using novel methodologies and the
generation of considerations/guidance stemming from these case studies. This document
reports the learnings and lessons obtained from the review experience of the four
case studies submitted to the 2015 review cycle of the IATA Case Studies project.
The topics discussed in this document include the strongest aspects and uncertainties
of each case study, and the document identifies areas for developing further guidance
on IATA.
Published on April 13, 2017
In series:OECD Series on Testing and Assessmentview more titles