The OECD webinars on Testing and Assessment Methodologies focus on selected ongoing projects that will result in the short to medium term in new methodologies to test and assess chemicals. These free webinars are open to potential end users among regulators and contract research organisations who want to get familiar with new standards and approaches. Video recordings of our webinars are made available online afterwards.
SAVE THE DATE: WEBINAR on HOW TO ASSESS EXPOSURE TO NANOMATERIALS? The evaluation result of existing tools/models
WHEN: 2 December 2021 at 14:00 -16:00 CET / 08:00 - 10:00 EST
The webinar will be held in English and Spanish.
With the dramatic increase of nano-enabled products entering the market every year, human and environmental exposures are inevitable, which raises concerns in terms of the health and safety of such emerging nanomaterials. Scientific knowledge to assess the exposure to nanomaterials continues to improve. As an example, new exposure tools and models for nanomaterials are being developed.
To further promote the development in this area, the OECD compiled an inventory of available models and tools for assessing occupational, consumer and environmental exposure to Nanomaterials. 54 tools and models were initially compiled and following in-depth analyses, 10 occupational, 7 consumer and 6 environmental tools/models were recommended or evaluated as suitable for assessing exposure to nanomaterials. The detailed information on the analyses and evaluations are provided in the reports accessible from the Series on Nanomaterials website (No. 98, 99, 100 and 101).
The OECD will be hosting a webinar on 2 December at 14:00 CET. Tune in to hear the researchers present the key findings of the reports.
Speakers and presentations:
watch the WEBINAR replay on the implementation of the defined approaches on skin sensitisation
Humans and the environment are exposed every day to chemicals. How do we make sure that these chemicals are safe?
Industry is required to test these chemicals to understand how they may affect people and the environment. In the past, these tests were most commonly carried out on animals. As scientific methods and tools progress, the use of animals to test a product designed for humans are becoming obsolete, in addition to being unethical. With new methods being developed, it is possible to perform these tests on human and animal cell cultures with equally rigorous and robust results. Because the OECD is committed to chemical safety and animal welfare, a new ground-breaking Guideline on Defined Approaches for Skin Sensitisation (OECD GL 497) was released on 14 June 2021. It is the first ever Guideline that uses non-animal methods to predict whether a chemical can cause skin allergies.
The OECD organised a webinar on 18 October 2021 to discuss the implementation of the Defined Approaches on Skin Sensitisation for chemical safety in member countries. This webinar paved the way for companies and authorities to determine the environmental toxicity of chemicals without having to resort to animal testing.
Speakers and presentations
Access the Question and Answers document here.
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Webinar on Physiologically Based Kinetic (PBK) Models
10 May 2021: Gaining acceptance in next generation PBK modelling approaches for regulatory assessment
The OECD presented the recently published Guidance Document on the Characterisation, Validation and Reporting of Physiologically Based Kinetic (PBK) Models for Regulatory Purposes. This guidance aims to increase the confidence in the use of PBK models parameterised with data derived from in vitro and in silico methods, and help address “unfamiliar” uncertainties associated with these methods.
The webinar introduced the assessment framework for PBK models that was developed to evaluate the attributes and uncertainties of these models, including a dedicated discussion on sensitivity analysis. It also focused on the scientific workflow for characterising and validating PBK models together with a template for documenting PBK models in a systematic manner and a checklist to support model evaluation. Access the presentation here.
Webinars on Adverse Outcome Pathways (AOPs)
30 January 2020: AOP knowledge base and AOP developing tips | Presentations:
30 April 2019: Adverse Outcome Pathway (AOP) framework | Presentations:
Webinars on Testing and Assessment Methodologies:
Webinars on Nanomaterials:
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