Join us on Friday 27 September 2019 @ 1 pm (CEST, Paris time) / 7 am (EST) to learn about various alternative test methods developed as OECD Test Guidelines, and relevant guidance material to address eye irritation and serious eye damage for hazard classification of chemicals.
The OECD Guidelines for the Testing of Chemicals are a unique tool for assessing the potential effects of chemicals on human health and the environment. They are regularly updated with the assistance of thousands of national experts from OECD member countries. The current deadline for comments is set on 19 September 2019 for the Draft Guidance Document dissolution rate and dispersion stability of nanomaterials.
Consult the January and February 2019 deadlines for comment of various OECD Guidelines for the Testing of Chemicals: in Vitro 3T3 NRU phototoxicity test; Vitrigel Eye Irritancy Test Method; in vitro Macromolecular Test Method for Eye Hazard Potential; and In Chemico Skin Sensitisation Assays addressing the AOP Key Event of covalent binding to proteins.
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This new edition of the OECD work on Chemical Safety and Biosafety highlights the activities, results and ongoing projects as outlined by the 2019-2020 work programme.
This page contains a list of the Guidelines for the Testing of Chemicals.
On 11 February 2019, the OECD organised a webinar to learn and discuss new methodologies on liver models for induction, clearance and toxicity. The speakers presented the benefits compared to existing methods in place, the types of chemicals tested, the results obtained, the transferability and economic aspects for routine testing, and any known limitation to the technologies and their applications.
The OECD has published the Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.
The first report is a synthesis from a Workshop on Approaches to Support Substitution and Alternatives Assessment, which discussed approaches used to support alternative assessments and substitution. The second report is a Cross Country Analysis of Approaches to Support Alternatives Assessment and Substitution of Chemicals of Concern that describes a list of approaches developed across countries and by different stakeholders.
The series on endocrine disrupters provides common tools and guidances for testing the effects of endocrine disrupting chemicals on the oestrogen, androgen and thyroid hormone systems. Using these validated methodologies, regulatory authorities can use internationally harmonised tools to evaluate chemicals of concern for human health and/or the environment as well as testing costs.