The OECD has published the second edition of the guidance on grouping of chemicals. This edition has been augmented with experience and examples encountered in the OECD Cooperative Chemicals Assessment Programme. It also introduces new or revised guidance on elaborating the analogue and category approach, quantitative and qualitative read-across, justifying read-across, and using bioprofiling results for grouping chemicals.
The OECD has published a guidance for characterising oleochemical substances. The method presented gives guidance on how these complex substances can be characterised in a way that their composition is accurately and consistently reflected to ensure that substances with the same chemical composition, manufactured in different countries, can be characterised with the same description for hazard assessment purposes.
This document provides information on the sources, use patterns, and potential release pathways of chemicals used in the manufacture of thermal and carbonless copy paper. It presents approaches for estimating the environmental releases of and occupational exposures to additives and components used in thermal and carbonless copy paper coatings.
eChemPortal uses are encouraged to respond to the on-line survey. Your use of the portal, your expectations, information, substance search, property search, structure search, design and layout. Your answers will help us improve eChemPortal - the Global Portal to Information on Chemical Substances, worldwide source of information about chemicals from authorities and international organisations, to meet your needs.
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The Programme has helped member countries and industry pool resources to assess the hazards of over 1200 industrial chemicals in its 22-year history, and has contributed to the development of many tools and techniques used in the assessment of chemicals around the world.
The OECD has published a revision of the 2003 Emission Scenario Document on Wood Preservatives to take into account the experience gained in working with the 2003 ESD. The document has been totally restructured, emission scenarios have been updated and new, niche scenarios have been added. The document is an essential tool for Member countries working in the area of biocidal products assessment.
This document outlines the methodologies and tools currently used to assess the risk of chemicals to children’s health and also identifies possible needs for additional guidance or tools based on the results of an on-line survey conducted in November 2011. The following areas of risk assessment are covered: definitions, hazard and exposure assessment, risk characterisation, cohort studies and combined exposure to multiple chemicals.
The Gefahrstoffdatenbank der Länder, a german database, is now linked to eChemPortal. 102545 substance records can be searched through the substance search. This includes German hazardous substances legislation as well as other sources reflecting the state of technology and occupational health and safety relating to activities involving hazardous substances. In addition, it contains links to various other German data bases.
Four new tutorials are available that provide illustrated examples for the use of the functionalities of the Query tool , the AOP workflow for Skin Sensitization, the information form the ECHA CHEM database and the capability to analyse tautomeric structures. The examples cover both human health (skin sensitisation) and environmental (acute aquatic toxicity to fish) endpoints.
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11/07/2013 –Recently the OECD released the third generation of the QSAR Toolbox. For this purpose, the guidance document for grouping chemicals to fill data gaps for acute aquatic toxicity have been updated. This guidance document should support the user of the QSAR Toolbox to build categories that are mechanistically and structurally robust.